22 November 2013

Frederick Sanger, double Nobel winner, dies at 95

Frederick Sanger, double Nobel winner, dies at 95


British biochemist Frederick Sanger, who twice won the Nobel Prize in chemistry and was a pioneer of genome sequencing, has died at the age of 95.

The laboratory praised Sanger, who died in his sleep Tuesday at Addenbrooke’s Hospital in Cambridge, as an “extremely modest and self—effacing man whose contributions have made an extraordinary impact on molecular biology.”

Sanger was one of just four individuals to have been awarded two Nobel Prizes; the others being Marie Curie, Linus Pauling and John Bardeen.

Jeremy Farrar, director of the Wellcome Trust, called Sanger “the father of the genomic era.”

Sanger first won the Nobel Prize in 1958 at the age of 40 for his work on the structure of proteins. He had determined the sequence of the amino acids in insulin and showed how they are linked together.

That work led to Sanger’s second Nobel Prize, awarded jointly in 1980 with Stanford University’s Paul Berg and Harvard University’s Walter Gilbert, for their work determining base sequences in nucleic acids.

Venki Ramakrishnan, deputy director of the MRC Laboratory, said it would be “impossible to overestimate the impact” Sanger had on modern genetics and molecular biology.

Sanger was born on Aug. 13, 1918, in Gloucestershire, southwestern England. While he initially planned to study medicine like his father, he switched fields and earned a degree in natural sciences from Cambridge University 1939. A conscientious objector in World War II, he went on to earn a PhD working on protein metabolism from the same university.

In addition to the Nobel Prizes, Sanger was made a fellow of the Royal Society in 1954, Commander of the Order of the British Empire in 1963 and the Order of Merit in 1986.

Sanger declined a knighthood, however, because he preferred not to be called “sir,” according to the laboratory he helped found.

According to The Sanger Institute, when he was asked if he would mind an institute being named after him, Sanger agreed but said “It had better be good.”

Sanger is survived by three children Robin, Peter and Sally.

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Criminality in the Indian political system

Criminality in the Indian political system

In their own long-term interest, all political parties must jointly agree to stop sponsoring criminal candidates

Criminality in politics, or more pointedly, criminals sitting in our Parliament and legislatures, is an issue that has for long been debated in many forums and has also been at the forefront of reform proposals sent by the Election Commission of India (ECI) to the government. With elections to five States under way, and the 16th General Election due to be completed before May 31, 2014, India is now gripped by that special fever that besets us every five years. Unexpectedly, part of the backdrop already stands influenced by a few recent decisions of the Supreme Court.

The Supreme Court has importantly passed three orders that relate directly to the conduct of elections. The first relates to the distribution of “freebies”, wherein the ECI has been asked to frame guidelines in consultation with political parties. The second is directing the installation of the None-of-The-Above (NOTA) button in the Electronic Voting Machines, which has already been implemented in the current round of Assembly elections. The third is the court’s order of July 10, 2013 in the Lily Thomas vs Union of India matter, wherein the Supreme Court has declared unconstitutional Section 8 (4) of the Representation of the People Act, 1951. The importance of this order cannot be overemphasised. The position that prevailed before this order was enacted was that all convicted MPs and MLAs enjoyed a three-month period in which to appeal against their conviction, and during this period they crucially retained their memberships in Parliament or legislatures respectively. What has changed is that while they still have the right to appeal, now they immediately cease to be members the House. While previously they were able to file appeals within the stipulated three months without giving up their membership, they managed, in effect, to remain MPs or MLAs often for long years after their terms had expired. Not only have these orders already impacted the elections under way but they will continue to have a profound impact on cleansing our political system.

The Lily Thomas matter was applied by the court prospectively and not retrospectively. The court would have had many reasons not to apply its order retrospectively, not the least of which is that it would possibly have thrown our current polity into disarray. Be that as it may, in the present and future, every parliamentarian or legislator who stands convicted for an offence that leads to a sentence of imprisonment for two years and more, will also be debarred from contesting an election for six years after his or her prison term ends. Moreover and equally importantly, there are offences which are already on the statute book and where conviction (even without sentence of imprisonment) leads to disqualification. These include conviction for rape, for promoting enmity and hatred between and among different classes or groups, conviction relating to bribery, and conviction under the Prevention of Corruption Act, the Foreign Exchange Regulation Act (FERA) and The Prevention of Terrorism Act, 2002 (POTA). Once again, since the grace period for remaining an MP or MLA has ended, this in effect means that the six year axe of debarment comes immediately into operation in these categories of cases as well.

Criminals among MPs, MLAs

Close on the heels of this order, the nation witnessed the jailing of Lalu Prasad, the president of a once nationally recognised political party, the RJD, as well as Rasheed Masood, a former Minister and sitting MP of the Rajya Sabha. While both stand debarred from contesting elections for six years after their jail terms are completed, in effect such a long banishment might well put an end to their political careers. For, as is well known, politics abhors a vacuum.

The abhorrence of criminality in politics is a common thread running through practically every student audience I have addressed across India in the last seven years. They are well aware of the figures compiled by non-governmental organisations such as NEW and ADR from the affidavits submitted to the ECI by contestants. Two vital orders of the Supreme Court in 2002 and 2003 made it compulsory for all candidates to file information regarding any and all criminal cases pending against them, as well as figures of the combined wealth or assets of the candidates and their spouses, and indeed their educational qualifications. With this information, the court hoped that voters could make informed choices about whom to vote for or not. Most of my student audiences knew the statistics; that in the present Parliament as many as 30 per cent of sitting Lok Sabha MPs and 31 per cent of Rajya Sabha MPs have criminal cases pending against them, that the Bihar Assembly (2010) has a high of 58 per cent criminals among its MLAs, while the Uttar Pradesh Assembly (2012) has 41 per cent. The Congress has 21 per cent declared criminals; the Bharatiya Janata Party has 31 per cent. At the other extreme, the Jharkhand Mukti Morcha has 82 per cent criminals among its MPs and MLAs.

Is it any surprise then that student audiences inevitably ask what is the point of clean election processes if the end result is to elect tainted men and women?

When the government decided to rush headlong into enacting an Ordinance to counter the July 10, 2013 Order of the Supreme Court, this resulted in a surge of public sentiment bordering on revulsion, against what would arguably have been a very regressive step in the development of our democratic institutions. The dramatic demise of the proposed Ordinance ironically became a critically important milestone in the strengthening of our democratic edifice, which I think many of us realise is still a work in progress.

Three issues

In the rash of commentaries that followed the Supreme Court Order of July 10, followed in turn by the legislative proposals sought to be placed before the winter session of Parliament and finally by the Ordinance that the Cabinet cleared, I would like to comment on three issues. First, it is no secret that many politicians have their own criminal elements to protect and whom they need to use in elections to round up voters. They spend clandestinely and sometimes devise mafia-like strategies to reinforce the “winnability” concept that has now come to be the “mantra” which has displaced any truly democratic relationship between candidates and the public whom they seek to represent. Hence the political establishment quickly closed ranks in favour of the Ordinance.

The second issue to my mind was whether the President (who called in senior Ministers for consultation to raise questions and seek clarifications), would have signed this Ordinance, or whether he would have just let it asphyxiate itself.

The third issue is that it took Rahul Gandhi to speak out and publicly criticise the Ordinance. In the aftermath of his intervention, the cacophony of opinions on our news channels reached a crescendo. One of the few voices that I managed to hear over the din of panellists and anchors, was that of The Hindu’s N. Ram, who cut aside all rhetoric on the non-use of parliamentary language by saying, “Rahul Gandhi single-handedly killed the wretched Ordinance. Instead of acknowledging that, do we need to make a fuss about the words he used?”

For what we must also recognise is that if this Ordinance had been passed, it would have officially endorsed that criminality in parliamentary ranks was perfectly acceptable. It would also have rendered our elected representatives even more distant from our people. Not only that, it would almost certainly have put the Executive and the Supreme Court on a collision course, leading to unnecessarily troubled relations between vital institutions. We have only to look in our own neighbourhood to understand how such conflicts have in varying measure stunted the growth of democratic structures.

I read in the press with increasing disappointment that many political leaders and parties including the Congress and the BJP have since given the ticket in these elections to either criminals or to their family members as proxies. This, sadly, concedes the “winnability” factor over “clean” politics.

Surely the time is finally here for all political parties to jointly agree to step away from sponsoring criminal candidates. It would be in their long-term interest to do so, because now some ground realities have changed, for upon conviction such candidates would have to resign anyway and make way for by-elections. In the short-term, they may win an election, but in the longer term they will, once again, strike a blow to the development of a healthy, wholesome and robust democracy that our freedom fighters fought for, and our constitutional framers had envisaged.

TOPPERS STORY

Shuchita Kishore, IAS Topper 2010: You are all alone at some point during the struggle

Young woman from Lucknow, Shuchita Kishore, who got 39th position in the Civil Services Exam 2010, spoke to Gulshan Sharma of jagranjosh.com

Shuchita’s is the story of an ordinary but determined girl. Drawing her inspiration from the interviews of IAS toppers and closely following their advice, this young woman from Lucknow finally realised her dream of becoming a civil servant in her third attempt. Shuchita means pure, simple and honest. That’s exactly how this slim and tall young woman of 27 comes across as she makes an effort to smile in front of the camera. Thoughtful and composed in her Salwar Kurta, the 39th ranker in the UPSC Civil Services exam 2010 opines that diplomacy must precede military action as she hopes to become an IFS officer.

One of the four daughters of retired UP government official Mr RK Srivastava, Shuchita could not clear the Prelims in her first attempt at the UPSC due to lack of proper guidance. The second attempt was encouraging as she managed to reach the interview stage. Finally in 2011, Shuchita’s efforts paid off as she secured 39th rank in the Civil Services exam 2010. The hard work clearly reflects in her eyes as she recalls, “It was not that easy to go in for three consecutive attempts but I derived strength from my belief in God.”

As she pursues her PhD in English Literature from Jawaharlal Nehru University in New Delhi, Shuchita takes pride in showing the copies of IAS interviews that she read way back in 2004 in Jagran Josh. The young diplomat in the making first decided to be a civil servant when she was in class 7 and considers 1996 UPSC topper Mr Iqbal Singh Dhaliwal and 2005 UPSC topper Mona Pruthi her role models. Shuchita loves reading literature and quizzing is her favourite hobby.

Education
Shuchita Kishore went through schooling in Lucknow where she scored 89% and 86% in her class 10 and 12 exams. She then joined Lucknow University from where she completed her BA in Political Science and English Literature with 67%. On graduating from the Lucknow University, she moved to New Delhi to do her Masters in English Literature from JNU. She is currently pursuing her PhD from the JNU itself, the library of which is popularly known as the UPSC hall. Shuchita recognises the importance of educational institutions known for excellence but does not shy away from saying, “It’s not the institutions that make individuals. It’s the people who make institutions.”

Advice to IAS aspirants

Quoting Rig-Veda, Shuchita says, “Let noble thoughts come to us from all sides.” She also identifies with Gandhi’s talisman as she understands the importance of a civil servant whose decisions can affect the entire nation in some way or the other. Shuchita has a word of advice for IAS aspirants as she suggests, “Think about the nation. Try to develop a vision. Never lose hope and with strong determination and hard work, there is nothing that will stop you from succeeding in UPSC exam and life.” She further adds, “You could well be the first person from your school or college to crack the Civil Services exam.”
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SAMVEG IAS DEHRADUN

1 November 2013

HAPPY DIWALI TO ALL DEAR FRIENDS AND STUDENTS


HAPPY DIWALI


HAPPY DIWALI

Diwali is the festival of lights, but we end up adding waste and pollution to our environs. Other than lighting of lamps, drawing rangolis and feasting on sweetmeats, festivities involve bursting of crackers and playing with sparklers during the entire span of 3-5 days, usually between mid-October and mid-November.

Wide range of chemicals right from cellulose nitrate, charcoal, sulphur and potassium nitrate present as ingredients in the fire-crackers and sparklers, give off a range of pollutants when they are burnt. Suspended Particulate Matter (SPM), Respirable Suspended Particulate Matter (RSPM), Oxides of Nitrogen and Sulphur Dioxide levels in the atmosphere which indicate air quality almost double and sometimes treble during Diwali. Added to this, falling temperature and wind velocity during these days slows down pollutant dispersal and further ups the levels of pollutants. This in turn is enough to cause respiratory distress to even otherwise healthy individuals, forget the asthmatics who usually suffer the most when air pollution increases. Heavy smog hangs low in the air on Diwalinight and a few days after that.

In the long run, air pollution can lead to lung cancer, cardiovascular diseases, chronic respiratory diseases, and allergies in adults. It can also cause acute respiratory infections in children.
·         Suspended particulate matter can cause asthma, bronchitis, and other respiratory disease.
·         Sulfur dioxide can damage lungs and lead to lung disorders like wheezing and shortness of breath.
·         Oxides of Nitrogen can cause skin problems, eye irritation, and cause respiratory problems in children.
·         Chemicals used in crackers like lead, magnesium, cadmium, nitrate, sodium, and others can have various harmful effects.
·         Heavy metals remain in the atmosphere for long and then get oxidised before entering the food chain through vegetables

It’s not just atmospheric pollutants, but the noise levels of the bursting crackers also deserve special mention. Human ears can only tolerate sounds upto 85 decibels but the sounds of crackers exceed 140 decibels.  The number of noisy crackers is usually more in Diwali which causes a lot of discomfort to heart patients and the elderly. Noise pollution can cause hearing loss, high blood pressure, heart attack and sleep disturbances. Hence, Crackers should not be burst outside hospitals, old age homes and residences of heart patients. The Union Environment and Forest Ministry had issued notification on October 5, 1999, besides; the Supreme Court had also issued instructions for the prevention of pollution from loudspeakers and other instruments making high sound and firecrackers. In these instructions, it is stipulated to ban firecrackers having more than 145 decibel sound.
The amount of garbage released on the day after Diwali is phenomenal. Approximately 4,000-8000 additional metric tonnes of garbage are released in each metropolis during Diwali celebrations. And this garbage is extremely hazardous for the environment as it comprises of chemicals like phosphorous, sulphur and potassium chlorate, and tonnes of burnt paper.  Many people get injured in fire accidents caused by the crackers every year. Most of the victims are children in the age group of 8-16.  
However, Diwali can be made safer and happier if certain precautions are taken during celebrations. To mention few, crackers producing noise should not be burst between 10 PM. and 6 A.M; crackers which bear the Supreme Court instructions and noise pollution levels alone should be purchased; prohibit use of crackers in areas within 100 meters of hospitals, educational institutions, courts and religious places);spread awareness about the noise and air pollution that they cause; protect your children by avoiding loud noise. Minor damage at a young age can lead to major hearing loss and refrain from buying fire crackers which exceed prescribed noise limit.
Crackers cause tremendous air and noise pollution, trouble animals and infants, old and cause fatal accidents. There are other ways like lighting Diyas, distributing sweets, gifts, through which we can celebrate our festivals.Diwali is a festival to enjoy and celebrate, but we should not celebrate it at the cost of someone else’s ill-health and discomfort. No doubt, these days awareness with regards to pollution is on the rise and cracker sales are coming down,  but let’s pledge “cracker-free Diwali” and motivate friends and relatives to promote ‘No Crackers’ campaign. This will help save environment and also make this literally a festival of lights than a festival of noisy fire-crackers!

Happy, colourful, bright Diwali!!!!!!!!!!!!!!!!!!!

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